Damaged sperm parameters and spermiation failure in venlafaxine-treated rats: a correlation with high testicular aromatase immunoexpression and reduced epididymal V-ATPASE
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منابع مشابه
Protective Effect of Spirulina and Phycocyanin on Testicular Tissue and Sperm Parameters in Adult Rats Treated with Hydrogen Peroxide
Background and purpose: About 50% of infertility in couples is related to male factors and oxidative stress is one of the main causes of infertility in men. Hydrogen peroxide has an adverse effect on male reproductive system due to its free radicals. Spirulina and phycocyanin are known to have antioxidant properties and can modify stressors. Materials and methods: In this experimental study, ...
متن کاملRat testicular germ cells and epididymal sperm contain active P450 aromatase.
Although testosterone is the principal sex steroid produced by the testis, estrogen is known to be produced by both Leydig and Sertoli cells during different developmental periods. Additionally, evidence is unfolding to suggest that germ cells might also participate in the synthesis of estrogen within the male reproductive tract. We have recently reported that the messenger ribonucleic acid (mR...
متن کاملDiethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology.
In this study, we characterized estrogenic effects of diethylstilbestrol (DES) on reproductive parameters in male rats to identify a minimal dose level that alters epididymal and sperm functions but has little or no effect on sperm production and/or spermatogenesis. Adult rats (five animals/group) received s.c. injections of 0.2 ml of corn oil containing DES at a rate of 1.0 mg, 200 microg, 40 ...
متن کاملSaffron Improves Epididymal Sperm Parameters in Rats Exposed to Cadmium
BACKGROUND Cadmium (Cd) is known to cause various disorders in the testis. The general population may be exposed to Cd through ingestion of food and drinking water, inhalation of particulates from ambient air, tobacco smoke and ingestion of contaminated soil and dust. Saffron (Crocus sativus L.) is widely used as a food flavour, and has well known medicinal effects. OBJECTIVES The aim of this...
متن کاملCorrelation between Hyponatremia and High Risk Clinical and Echocardiographic Features in Patients with Acute Heat Failure
Background and purpose: Heart failure (HF) is characterized by decreased ability of the heart to provide sufficient blood flow or fill with the blood. Hyponatremia is the most commonly seen electrolyte abnormality in patients with heart failure that is associated with increased morbidity and mortality. The aim of this study was to assess the correlation between hyponatremia and high risk clinic...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2019
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2019.08.017